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A Prospective Study on the Financial Impact of Breast Cancer Treatment over a One-Year Period for Patients at a Rural Cancer Center

Manko, C. D.; Khan, K.; Zlupko, T.; Witteveen, N.; Thresher, E.; Panek, J.; Inamdar, A.; Perry-Keaty, C.

2025-05-08 oncology
10.1101/2025.05.07.25326315 medRxiv
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PurposePatients undergoing breast cancer treatment experience financial burden that can lead to stress and affect access to care. This study investigates the financial burden patients with breast cancer face. MethodsChange in level of self-reported financial burden was evaluated by determining the difference of the Comprehensive Score for Financial Toxicity-Functional Assessment of Chronic Illness Therapy (COST-FACIT). The survey was administered at baseline, 3, 6, and 12 months to patients undergoing treatment within a rural cancer center to understand patterns with financial burden. A higher score indicated less financial toxicity. Health insurance literacy data (at baseline and 1 year) and support services data (at baseline, 3, 6, and 12 months) were also collected through survey distribution. Demographic data were also collected. ResultsCOST-FACIT scores significantly increased over the course of the year (p < 0.001) and for patients at or above the age of 65 years (p = 0.001). There was no statistical difference between insurance type (private or public) or between the stages of breast cancer. ConclusionCOST-FACIT scores were higher with treatment over time and if the patient was 65 or over. Implication for Cancer SurvivorsAdditional financial support should be provided to patients, especially early on in their cancer treatment, with special focus given to patients under the age of 65. This support could help effectively mitigate financial burden.

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