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Inter-brain similarity and connectivity based on EEG hyperscanning during patient-acupuncturist interactions

Wang, G.

2025-05-03 neuroscience
10.1101/2025.04.29.651215 bioRxiv
Show abstract

The study of patient-clinician relationships is a vital branch of interpersonal interaction research. Acupuncture attaches great importance to positive patient-clinician interactions; thus, it serves as a typical example of patient-clinician interaction research. Based on electroencephalography (EEG) hyperscanning, this study explored inter-brain similarity based on spatial correlations between two brains as well as inter-brain connectivity of different regions through different frequency bands. Regarding inter-brain similarity, both acupuncture and sham acupuncture significantly decreased spatial correlation during certain sessions during acupuncture. Regarding inter-brain connectivity, acupuncture enhanced not only the connectivity of the beta frequency band in the right temporoparietal regions but also the connectivity of the fast-ripple frequency band in the right and left temporoparietal regions. These results suggest that inter-brain similarity should be emphasized in patient-clinician relationship research. Moreover, high-frequency oscillations (HFOs) potentially play an important role in inter-brain connectivity in addition to the classical EEG low-frequency bands.

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