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Hypertrophic Cardiomyopathy -- The Impact of Age at Diagnosis of the Proband on Genetic Yield, Clinical Presentation, Outcomes, and Yield of Family Screening
2025-04-21
cardiovascular medicine
Title + abstract only
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BackgroundHypertrophic cardiomyopathy (HCM) is a complex disease with variable clinical presentation and familial impact. Age at diagnosis may influence phenotypic expression, but it is unclear if age also affects clinical outcomes, genetic findings, and yield of family screening. MethodsRetrospective cohort study of families screened for HCM in Eastern Denmark (2006-2023). Probands were analyzed by age at diagnosis both continuously and in quartiles: 18-45, 46-56, 57-65, and >65 years. Result...
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