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Long-Term Recall of Amyloid PET Results

Scanlan, M.; Hiegert, H.; Townley, R. A.; Almahgraby, A.; Key, M. N.; Morris, J. K.; Burns, J. M.; Vidoni, E. D.

2025-04-14 neurology
10.1101/2025.04.10.25325602 medRxiv
Show abstract

We assessed long-term recall and perceived impact of amyloid PET results among 92 cognitively normal adults who received structured result disclosure 6-9 years earlier. Two-thirds correctly recalled their result; only three misremembered the result as the opposite of what was communicated. Participants reported limited behavior change, though those with elevated scans more often endorsed lifestyle modifications. Perceived AD risk aligned with scan status but did not appear to cause lasting psychological distress. Most participants, regardless of result, viewed the experience positively and would undergo testing again. These findings support the long-term acceptability of disclosing amyloid PET results.

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