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Sociodemographic Determinants of Respiratory Failure in Patients Hospitalized with SARI in Cali, Colombia

Roa-Urrutia, P.; Valencia-Cardona, A. F.; Reina, C.; Guzman-Escarria, G.; Montoya-Salazar, J. I.; Garces-Hurtado, A.; Ortiz-Carrillo, M. E.; Arango-Londono, D.; Avila, G.; Cruz-Barbosa, S.; Concha-Eastman, A.

2025-04-10 epidemiology
10.1101/2025.04.08.25325483 medRxiv
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ObjectivesTo analyze the association between respiratory failure and sociodemographic determinants in patients hospitalized with Severe Acute Respiratory Infection (SARI) in Cali, Colombia, in 2022. MethodA descriptive and cross-sectional study was conducted using data from the 2022 respiratory failure notification file No. 348. A generalized linear model with an exponential binomial family was applied. Absolute frequencies, proportions, and odds ratios (OR) were estimated. ResultsOf 1,163 patients, 4.5% (n=52) developed respiratory failure. Those with high [OR: 2.03; 95%CI: 1.2-2.8] or medium-high [OR: 1.4; 95%CI: 0.9-3.7] vulnerability had a greater likelihood of respiratory failure compared to patients with low vulnerability. Asthma and COPD increased the risk [OR: 4.3; 95%CI: 1.5-6.03] and [OR: 3.3; 95%CI: 1.3-4.3], respectively. Sepsis was also identified as a significant risk factor [OR: 2.7; 95%CI: 1.8-3.5]. ConclusionsThe results emphasize the need for targeted public health actions. Sociodemographic factors, especially multidimensional poverty such as limited education, income, and healthcare access play a key role in respiratory failure outcomes.

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