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The effect of SARS-CoV-2 testing on healthcare seeking behaviour at primary care level: implications for COVID-19 vaccine effectiveness estimates in test-negative design studies.

2025-04-01 epidemiology Title + abstract only
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BackgroundDiagnostic (self-)testing for SARS-CoV-2 may lead to selection bias in test-negative case-control designs (TND) for COVID-19 vaccine effectiveness (CVE) at primary care level. We investigated whether after the acute phase of the pandemic, (self-)testing among those with an acute respiratory infection (ARI) was associated with healthcare seeking behaviour at primary care level in the general Dutch population. MethodsWe pooled questionnaire data from three study rounds (June 2022, Novem...

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