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Anti-oxidative stress therapies reduce chemotherapy-induced peripheral neuropathy in colorectal cancer patients treated with oxaliplatin: a systematic review and meta-analysis
2025-03-25
oncology
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Background and PurposeChemotherapy-induced peripheral neuropathy (CIPN) is a major side-eaect of many commonly used cancer drugs, aaecting up to 90% of patients treated with oxaliplatin. This systematic review and meta-analysis aimed to analyse randomised controlled trials (RCTs) to determine if any pharmacological agents can prevent or reduce oxaliplatin-induced peripheral neuropathy (OIPN) in colorectal cancer (CRC) patients. Materials and MethodsWe searched PubMed, EMBASE and Web of Science ...
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