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"Dynamic Analysis of Heart Rate Variability through Motion Path Analysis of the Poincare Plot"

Thakur, M.; Goswami, D. P.; Sarkar, K.; Sengupta, A.

2025-03-23 cardiovascular medicine
10.1101/2025.03.21.25324311 medRxiv
Show abstract

Autonomic Nervous System (ANS) maintains bodys homeostasis by regulating heart rate and other vital functions. Heart Rate Variability (HRV) analysis is a non-invasive method used to assess ANS activity by measuring variations between consecutive heartbeats. Poincare plot, a widely used HRV analysis tool, visualizes the relationship between successive heartbeats. However, conventional Poincare plot analysis primarily relies on static statistical descriptors, such as SD1 and SD2, which measure short-term and long-term variability but fail to capture the dynamic progression of heartbeat intervals. This paper introduces motion path analysis of the Poincare plot, a novel approach that tracks how heartbeat intervals evolve over time. By following the sequential movement of data points, this method reveals both short-term and long-term HRV trends. Our study demonstrates that motion path analysis detects subtle changes in heart rate patterns under different physiological conditions, such as rest and stress (e.g., head-up tilt tests). This technique offers a more comprehensive understanding of ANS activity by visualizing point-to-point transitions influenced by sympathetic and parasympathetic responses. Motion path analysis offers a new way to visualize and interpret the complex temporal fluctuations of ANS and has potential applications in clinical research, providing deeper insight into autonomic regulation in health and disease.

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