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Multimodal MRI Marker of Cognition Explains the Association Between Cognition and Mental Health in UK Biobank

2025-03-20 psychiatry and clinical psychology Title + abstract only
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BackgroundCognitive dysfunction often co-occurs with psychopathology. Advances in neuroimaging and machine learning have led to neural indicators that predict individual differences in cognition with reasonable performance. We examined whether these neural indicators explain the relationship between cognition and mental health in the UK Biobank cohort (n > 14000). MethodsUsing machine learning, we quantified the covariation between general cognition and 133 mental health indices and derived neu...

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