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Clinical Validation of the PSCOPE Hybrid Model Prediction of Left Ventricular Assist Device Implantation Hemodynamics: Three Patient-Specific Cases

2025-03-11 cardiovascular medicine Title + abstract only
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ObjectiveThe Physiology Simulation Coupled Experiment (PSCOPE) is a hybrid modeling framework designed for mechanistic cardiovascular predictive modeling. It couples a physical fluid experiment with a lumped parameter network simulation to replicate the closed-loop feedback between simulated cardiovascular physiology and fluid dynamics in the physical experiment. This study validates PSCOPEs predictions of post-surgical physiology against clinical data in the context of HeartMate 3 left ventricu...

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