Effects of Ultrasound Cycloplasty following Failed Surgery for Glaucoma: 12-months Results From a Prospective Clinical Study

ObjectivesThis prospective study aims to evaluate the outcomes and safety of Ultrasound Cycloplasty(UCP) in controlling intraocular pressure in patients with prior failed glaucoma surgeries. MethodsA total of 20 eyes from 19 patients who underwent UCP following failed glaucoma surgery between September 2020 to September 2022, were included. All patients were followed for over 12 months. Intraocular pressure, ocular hypotensive medications, and best-corrected visual acuity were recorded and compared after surgery. Complete success was defined as intraocular pressure within the range of 6-21mmHg after treatment, without the use of anti-glaucoma agents. Qualified success was defined the same as complete success but allows the presence of anti-glaucoma agents. ResultsAt 12 months follow-up, intraocular pressure decreased from 45.10{+/-}10.74 mmHg to 20.80{+/-}6.05 mmHg, representing a reduction of 53.88% (P < 0.01). The rates of complete successes and qualified successes were 20.00% (4 of 20 eyes) and 65.00% (13 of 20 eyes) 12 months after treatment respectively. ConclusionUCP is a safe and effective surgical approach for eyes with prior failed glaucoma surgeries.