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Identification of Poly-Metabolite Scores for Diets High in Ultra-Processed Food in an Observational Study with Validation in a Randomized Controlled Crossover-Feeding Trial

2025-02-19 nutrition Title + abstract only
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BackgroundUltra-processed food (UPF) accounts for a majority of calories consumed in the United States, but the impact on human health remains unclear. ObjectiveTo identify poly-metabolite scores in blood and urine that are predictive of UPF intake. MethodsIDATA participants (n=718) with serially collected blood and urine and up to 6 24-hour dietary recalls (ASA-24s), collected over 12-months, were selected for metabolomics analysis using ultra-high performance liquid chromatography with tande...

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