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Mild cognitive impairment cases affect the predictive power of Alzheimers disease diagnostic models using routine clinical variables

2025-02-06 neurology Title + abstract only
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Diagnostic models using primary care routine clinical variables have been limited in their ability to identify Alzheimers disease (AD) patients. In this study we sought to better understand the effect of mild cognitive impairment (MCI) on the predictive performance of AD diagnostic models. We sourced data from the Alzheimers Disease Neuroimaging Initiative (ADNI) cohort. CatBoost was used to assess the utility of routine clinical variables that are accessible to primary care physicians, such as ...

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