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Clinically actionable hypertrophic cardiomyopathy genes in South Asian Indians

2025-02-02 cardiovascular medicine Title + abstract only
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BackgroundPrimary hypertrophic cardiomyopathy (HCM) is predominantly a genetic disease causing left ventricular hypertrophy in the absence of other cardiac and systemic metabolic diseases. Currently, limited data exists on the prevalence of clinically actionable gene variants for primary HCM in South Asian Indians (SAI), that is necessary for minimizing disparities in interpreting ancestry-specific variants. ObjectivesThe ClinGen Hereditary Cardiovascular Disorders (HCVD) Gene Curation Expert P...

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