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Local olfactory nerve stimulation triggers patchy activation of columns across rat olfactory bulb

Jahan, I.; Kindler, L.; Reichardt, N.; Suyama, H.; Egger, V.

2025-01-29 neuroscience
10.1101/2025.01.29.635425 bioRxiv
Show abstract

Columnar organization is a hallmark of neocortical sensory areas, most prominently in primary somatosensory and visual cortex. In the olfactory bulb, the existence of a vertical columnar organization of circuits associated with glomerular input channels has been implicated by various approaches. Here, based on activity-dependent labelling and tissue clearing, we provide direct evidence for functional bulbar columns formed by mitral cells and granule cells that display a uniform morphology.

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