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Apathy progression is associated with brain atrophy and white matter damage in Parkinsos disease

2025-01-23 radiology and imaging Title + abstract only
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Apathy is a prevalent non-motor symptom that significantly impacts the quality of life in Parkinsons disease (PD) patients. Although previous studies have investigated the neural correlates of apathy in PD, the longitudinal relationships between regional brain atrophy, white matter hyperintensities (WMHs), and apathy progression remain underexplored. Using longitudinal, multisite data of de novo PD patients from the Parkinsons Progression Markers Initiative (PPMI), the present study aims to inve...

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