Short-term Outcomes of Trabeculectomy with Mitomycin-C in a Tertiary Eye Hospital in Nepal: A Prospective Descriptive Study

ObjectiveThis study evaluated the short-term outcomes of trabeculectomy with mitomycin-C in glaucoma patients at Tilganga Institute of Ophthalmology, Kathmandu, Nepal, between June 2021 and May 2022. MethodsThis was a prospective descriptive study, conducted on 56 eyes of 51 consecutive glaucoma patients who underwent trabeculectomy with mitomycin-C (0.02%). Follow-up assessments were carried out on postoperative day 1, week 1, month 1, month 3, and month 6. Statistical analysis was done using SPSS version 20 software. ResultsThe study included 38 male (74.5%) and 13 female (25.5%) patients with an average age of 43.50 {+/-} 15.45 years. A significant reduction in median intraocular pressure (IOP) from 24.33 mmHg preoperatively to 12.00 mmHg at 6 months postoperatively was observed (P < 0.01). The median number of anti-glaucoma medications decreased from 3.0 preoperatively to 0.0 at all postoperative visits. Complete surgical success was achieved in 85.7% of eyes. Common complications included shallow anterior chamber, hypotony, and IOP elevation. ConclusionTrabeculectomy with mitomycin-C demonstrated high surgical success rate with low complication rates in the short term, making it an effective and safe treatment option for glaucoma patients not medically controlled. It may benefit glaucoma patients facing challenges with long-term anti-glaucoma medication use and frequent follow-up visits, thus improving the management outcomes of this chronic condition.