Trace metals availability controls terminal electron acceptor utilization in Escherichia coli
Ricciardelli, A.; de Pins, B.; Brusca, J.; Correggia, M.; di Iorio, L.; Cascone, M.; Giardina, M.; Castaldi, S.; Isticato, R.; Iacono, R.; Moracci, M.; Nappi, N.; Pollio, A.; Vetriani, C.; Leone, S.; Cordone, A.; Giovannelli, D.
Show abstract
Trace metals play an essential role in the metabolism of all living organisms and many metal-containing enzymes contribute to key physiological and ecological processes such as aerobic and anaerobic respiration, photosynthesis, carbon and nitrogen fixation. Despite this, trace metals potential to control microbial functional diversity and metabolic shifts is unknown. Here we demonstrate that the availability of trace metals controls electron acceptors utilization in Escherichia coli. Physiological and proteomic data show that trace metals depleted cultures have significantly reduced growth, start fermentation and increase energy expenditure for metal homeostasis even when more energetically favourable electron acceptors are present. Overall these results suggest how evolutionary and competitive pressures arising from changes in biological trace metals availability in deep time have contributed to shaping evolution and competition.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- A role for glutathione in buffering excess intracellular copper in Streptococcus pyogenes 96%
- Systems-wide dissection of organic acid assimilation in Pseudomonas aeruginosa reveals a novel path to underground metabolism 96%
- Uncultivated DPANN archaea are ubiquitous inhabitants of global oxygen deficient zones with diverse metabolic potential 96%
Similar papers in this journal
- Trajectories for the evolution of bacterial CO2-concentrating mechanisms 96%
- The dynamic trophic architecture of open-ocean protist communities revealed through machine- guided metatranscriptomics 95%
- Coordination of gene expression with cell size enables Escherichia coli to efficiently maintain motility across conditions 95%
Similar papers in this journal
- Differential global distribution of marine picocyanobacteria gene clusters reveals distinct niche-related adaptive strategies 95%
- Halophilic microbial community compositional shift after a rare rainfall in the Atacama Desert 95%
- Soil microbial community response to corrinoids is shaped by a natural reservoir of vitamin B12. 94%
Similar papers in this journal
Similar papers in this journal
- Diversity and function of methyl-coenzyme M reductase-encoding archaea in Yellowstone hot springs revealed by metagenomics and mesocosm experiments 95%
- Culexarchaeia, a novel archaeal class of anaerobic generalists inhabiting geothermal environments 95%
- Selective enrichment of high-affinity clade II N2O-reducers in a mixed culture 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.