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PHIVE: A Physics-Informed Variational Encoder Enables Rapid Spectral Fitting of Brain Metabolite Mapping at 7T
2025-01-03
radiology and imaging
Title + abstract only
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Magnetic Resonance Spectroscopic Imaging (MRSI) enables non-invasive mapping of brain metabolite concentrations but remains computationally intensive and challenging due to a low signal-to-noise ratio (SNR) and overlapping spectral features. Traditional spectral fitting methods, such as LCModel, are time-consuming and often lack comprehensive uncertainty quantification. In this study, we propose Physics-Informed Variational Encoder (PHIVE), a novel deep learning framework that integrates physics...
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