Back

LUKB DT: A Web Tool for Quick and Efficient Identification of Disease Trajectories

Li, X.; Zhang, H.; Jiang, S.; Gao, B.; Hu, Z.

2025-01-02 epidemiology
10.1101/2025.01.01.25319864 medRxiv
Show abstract

As the volume of electronic medical data grows, understanding disease progression and identifying risk factors have become central to public health research. Disease trajectories provide valuable insights into disease progression and risk factors. LUKB DT (LUKB Disease Trajectories) is a user-friendly web tool designed to facilitate disease trajectory analysis using electronic medical records (EMR), particularly the UK Biobank data. LUKB DT processes EMR data, including patient ID, disease diagnoses, corresponding timestamps, and other relevant variables, combining Cox regression, binomial tests, and conditional logistic regression to identify disease trajectories. This tool offers a quick and efficient way to prepare and analyze disease trajectories, contributing to the expanding field of disease trajectory research and providing valuable insights for risk factor identification and disease progression studies. Detailed deployment and usage can be found in the Supplementary Material. LUKB DT is freely available at https://github.com/HaiGenBuShang/LUKB.

Matching journals

The top 7 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.