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Association Between Oral Microbiota and Close-Range Proximity in a Primary School

Dall'Amico, L.; Bai, X.; Weltzien, S. M.; Rayner, S.; Paolotti, D.; Budin Ljosne, I. S.; Matussek, A.; Furberg, A.-S.; Cattuto, C.; Sivert Nielsen, C.

2024-12-27 microbiology
10.1101/2024.12.27.628096 bioRxiv
Show abstract

The microbiota is the ensemble of microorganisms inhabiting the human body and it deeply influences human health and well-being. Recent studies showed its interplay with social behavior, suggesting that part of the microbiota might be socially transmissible. In this work, we investigate the association between close-range proximity and the oral microbiota composition in a group of children attending primary school. Unlike most related studies, our cohort comprises non-cohabiting individuals, and we use high-resolution proximity sensors to objectively measure social interactions. Our analysis shows that prolonged interactions between children pairs correlate with a higher similarity between their oral microbiota. These findings complement what is known for co-habiting individuals, suggesting that microbiota might be transmitted in social settings.

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