Repeated head-exposures to a 5G-3.5 GHz signal do not alter behavior but modify intracerebral gene expression in adult male mice.
Lameth, J.; Royer, J.; Martin, A.; Marie, C.; Arnaud-Cormos, D.; Leveque, P.; Poirier, R.; Edeline, J.-M.; Mallat, M.
Show abstract
The 5th generation (5G) of mobile communications promotes human exposures to electromagnetic fields exploiting the 3.5 GHz frequency band. We have analyzed behaviors, cognitive functions and gene expression in mice submitted to asymmetrical head-exposures to a 5G-modulated 3.5 GHz signal. The exposures were applied 1h daily, 5 days per week over a six-week period, at a specific absorption rate (SAR) averaging 0.19 W/kg over the brain. Locomotor activity in an open-field, object-place and object recognition memories were assessed repeatedly after four weeks of exposure and did not reveal any significant effect on the locomotion/exploration, anxiety level or memory processes. mRNA profiling was performed at the end of the exposure period in two symmetrical areas of the right and left cerebral cortex in which the SAR values were 0.43 and 0.14 W/kg, respectively. We found significant changes in the expression of less than 1% of the expressed genes with over-representations of genes related to glutamatergic synapses. The right cortical area differed from the left one by an over-representation of responsive genes encoded by the mitochondrial genome. Our data show that repeated head-exposures to a 5G-3.5 GHz signal can trigger mild transcriptome alterations without change in memory capacities or emotional state.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Exposure to 1800 MHz LTE electromagnetic fields under proinflammatory conditions decreases the response strength and increases the acoustic threshold of auditory cortical neurons. 95%
- Lack of pulmonary fibrogenicity and carcinogenicity of titanium dioxide nanoparticles in 26-week inhalation study in rasH2 mouse model 94%
- Carcinogenicity and testicular toxicity of 2-bromopropane in a 26-week inhalation study using the rasH2 mouse model 93%
Similar papers in this journal
- Repeated exposure to nanosecond high power pulsed microwaves increases cancer incidence in rat 96%
- Deviation from mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation 93%
- Comparative study between radiofrequency-induced and muscimol-induced inhibition of cultured networks of cortical neuron 93%
Similar papers in this journal
- Screening of metabolism-disrupting chemicals on pancreatic alpha-cells using in vitro methods 92%
- p16-3MR: a novel model to study cellular senescence in cigarette smoke-induced lung injuries during aging 90%
- SCREENING OF RELEVANT METABOLISM-DISRUPTING CHEMICALS ON PANCREATIC β-CELLS: EVALUATION OF MURINE AND HUMAN IN VITRO MODELS 90%
Similar papers in this journal
- Rapid loss of fine motor skills after low dose space radiation exposure 94%
- Behavioral profiling of hyperbaric oxygen as an intervention for chemotherapy-related functional impairments in male and female mice 91%
- Effects of working memory training on cognitive flexibility, dendritic spine density and long-term potentiation in female mice 90%
Similar papers in this journal
- Effects of head-only exposure to 900 MHz GSM electromagnetic fields in rats : changes in neuronal activity as revealed by c-Fos imaging without concomitant cognitive impairments 97%
- Impaired response to mismatch novelty in the Li2+-pilocarpine rat model of TLE: correlation with hippocampal monoaminergic inputs 92%
- Breathome discriminate Ischemic Heart Disease 89%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.