Back

Integration of Elemental Imaging and Spatial Transcriptomic Profiling for Proof-of-Concept Metals-Based Pathway Analysis of Colon Tumor Microenvironment

2024-12-10 pathology Title + abstract only
View on medRxiv
Show abstract

The complex interplay between metal abundance, transport mechanisms, cell distribution, and tumor progression-related biological pathways (e.g., metabolism, collagen remodeling) remains poorly understood. Traditionally, genes and metals have been studied in isolation, limiting insights into their interactions. Recent advances in spatial transcriptomics and elemental profiling now enable comprehensive exploration of tissue-wide metal-gene interactions, though integration remains challenging. In t...

Predicted journal destinations

1
Nature Communications
483 training papers
Top 7% 12.0%
2
iScience
74 training papers
#1 9.5%
3
Cancers
57 training papers
Top 2% 9.5%
4
Scientific Reports
701 training papers
Top 26% 7.9%
5
PLOS ONE
1737 training papers
Top 75% 6.0%
6
eLife
262 training papers
Top 11% 3.9%
7
BMC Cancer
21 training papers
Top 2% 2.0%
8
Cell Reports
25 training papers
Top 0.2% 2.0%
9
JCI Insight
63 training papers
Top 3% 2.0%
10
PLOS Computational Biology
141 training papers
Top 8% 1.5%
11
npj Digital Medicine
85 training papers
Top 12% 1.5%
12
Brain
69 training papers
Top 8% 1.4%
13
Journal of Clinical Microbiology
77 training papers
Top 5% 1.4%
14
Microbiology Spectrum
86 training papers
Top 4% 1.4%
15
International Journal of Molecular Sciences
39 training papers
Top 4% 1.2%
16
Computers in Biology and Medicine
39 training papers
Top 8% 1.0%
17
The Journal of Molecular Diagnostics
24 training papers
Top 2% 1.0%
18
JAMA Network Open
125 training papers
Top 23% 1.0%
19
Cureus
64 training papers
Top 17% 1.0%
20
eBioMedicine
82 training papers
Top 9% 1.0%
21
Proceedings of the National Academy of Sciences
100 training papers
Top 16% 1.0%
22
Biomedicines
21 training papers
Top 3% 0.7%
23
The Lancet Digital Health
25 training papers
Top 2% 0.7%
24
Cell Reports Medicine
49 training papers
Top 7% 0.7%
25
Frontiers in Oncology
34 training papers
Top 6% 0.7%
26
mBio
34 training papers
Top 3% 0.7%
27
Communications Biology
36 training papers
Top 8% 0.5%