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Analysis of germline genetic variants that cause hereditary coloretal cancer in Bahia
2024-12-08
genetic and genomic medicine
Title + abstract only
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BackgroundColorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Approximately 10% of CRC cases are linked to hereditary germline variants. Understanding regional genetic predispositions is crucial for developing personalized medicine strategies. ObjectiveThis study aims to analyze pathogenic germline variants associated with polyposis and non-polyposis syndromes in individuals from Bahia, Brazil. MethodsA cross-sectional, obser...
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