Shortwave infrared imaging increases the number of lymph nodes and the number of positive lymph nodes in surgical pathology specimens - a 104-patient study
Jorns, J. M.; Smith, R. S.; Strenk, D.; Stauble, G.; Khelifa, S.; Seltzer, R.; Manuel, J.; Rosenbaum, M. W.; Almas, J.; Li, Z.
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AimsAdequate lymph node examination is key to accurate cancer staging. Lymph node search in surgical resection specimens is a challenging task because it can be labor intensive and inconsistent. This study investigates the effectiveness of shortwave infrared imaging technology in increasing the overall and positive lymph node numbers. Methods104 surgical resection specimens from two hospitals were first grossed with traditional manual palpation. The residual tissues were then grossed with the assistance of shortwave infrared imaging. The numbers of lymph nodes and positive lymph nodes within these two steps were documented and compared. ResultsIn 90 of the 104 cases (86.5%), shortwave infrared imaging assisted gross examination identified additional lymph nodes. In 11 of 104 cases (10.6%), shortwave infrared imaging assisted gross examination identified additional positive lymph nodes. ConclusionsShortwave infrared imaging increases the number of lymph nodes and the number of positive lymph nodes in surgical pathology specimens compared to traditional visual and manual dissection.
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