Parental income and psychiatric disorders from age 10 to 40: a genetically informative population study

BackgroundLower parental income is associated with more psychiatric disorders among offspring, but it is unclear if this association reflects effects of parental income (social causation) or shared risk factors (social selection). Prior research finds contradictory results, which may be due to age differences between the studied offspring. MethodsHere, we studied psychiatric disorders in the entire Norwegian population aged 10 to 40 between 2006 and 2018 (N = 2,468,503). By linking tax registries to administrative health registries, we described prevalence rates by age, sex, and parental income rank. Next, we grouped observations into age groups (adolescence, ages 10-20; early adulthood, 21-30; adulthood, 30-40) and applied kinship-based models with extended families of twins and siblings to decompose the parent-offspring correlation into phenotypic transmission, passive genetic transmission, and passive environmental transmission. ResultsWe found that lower parental income rank was associated with higher prevalence of nearly all psychiatric disorders, except for eating disorders, for both men and women at all ages from age 10 to 40. Comparing the top with the bottom paternal income quartile, the prevalence ratio of any psychiatric disorder was 0.47 among 10-year-olds and decreased to 0.72 among 40-year-olds. The parent-offspring correlation was -.15 in adolescence, -.10 in early adulthood, and -.06 in adulthood. The kinship-based models indicated that phenotypic transmission could account for 39% of the parent-offspring correlation among adolescents (p < .001), but with no significant contribution in early adulthood (p = .181) or adulthood (p = .737). Passive genetic and environmental transmission contributed to the parent-offspring correlation in all age groups (all ps < .001). ConclusionOur findings are consistent with a significant role of social causation during adolescence, while social selection could fully explain the parent-offspring correlation in adulthood. Key PointsO_LILower parental income is associated with more psychiatric disorders among offspring. C_LIO_LIThere are conflicting results whether this association reflects effects of parental income or shared risk factors. C_LIO_LIAnalysing over 2.4 million individuals, our study provides a comprehensive overview of psychiatric disorder prevalence across age, sex, and parental income rank. C_LIO_LIAfter accounting for shared genetics and environments, we find that parental income rank appears to be associated with psychiatric disorders in adolescence, but not in adulthood. C_LIO_LIThe findings support early interventions targeting socioeconomic disparities to reduce adolescent psychiatric disorders. C_LI