Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia
Abera, A.; Monsieurs, P.; Pareyn, M.; Beyene, D.; Tasew, G.; Aroni-Soto, A.; Belachew, M.; Geleta, D.; Adnew, B.; Gidey, B.; Tadesse, H.; G/Egziabhier, A.; Abubeker, R.; Ali, A.; Tafess, K.; Rinke de Wit, T.; van Griensven, J.; Dujardin, J.-C.; Wolday, D.; Domagalska, M. A.
Show abstract
We sequenced Leishmania tropica genomes directly from eight human skin samples collected in a newly emerging focus of cutaneous leishmaniasis in Somali region, Ethiopia. We found a new variant with unique genomic signatures of drug resistance. Genomic homogeneity in the sampled population demonstrates the occurrence of a L. tropica outbreak.
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