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Infections are not alike: the effects of covariation between individual susceptibility and transmissibility on epidemic dynamics

2024-10-12 epidemiology Title + abstract only
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Individual-level variation in susceptibility to infection and transmissibility of infection can affect population-level dynamics in epidemic outbreaks. Prior work has incorporated independent variation in susceptibility or transmissibility of individuals into epidemic compartmental models. Here, we develop and assess a mathematical framework that includes covariation in susceptibility and transmissibility. We show that uncorrelated variation in susceptibility and transmissibility leads to an eff...

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