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Phosphatidic Acid Mediated Sonodynamic Therapy Facilitates M1 Macrophage Osteoclastic Function and Alleviates Early Vascular Calcification
2024-10-11
cardiovascular medicine
Title + abstract only
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BACKGROUNDVascular calcification significantly influences the onset and outcome of cardiovascular events, yet no effective treatment currently exists. Dysfunction of osteoclastic macrophages contributes to the formation of calcification. Our previous studies have shown that sonodynamic therapy (SDT) can rapidly reverse atherosclerotic plaques by targeting macrophages. This study aimed to investigate the effect of SDT on reducing early or mild vascular calcification by modulating the function of ...
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