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Multi-ancestry GWAS of Long COVID identifiesimmune-related loci and etiological links to chronic fatigue syndrome, fibromyalgia and depression

2024-10-09 genetic and genomic medicine Title + abstract only
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The etiology of Long COVID is poorly understood despite its estimated global burden of 65 million cases. There exists a paucity of genetic studies that can shed light on potential mechanisms leading to Long COVID. Using consented and genotyped data from 23andMe adult research participants, we conducted the largest multi-ancestry meta-analysis of genome-wide association studies of Long COVID across European (42,899 cases, 94,721 controls), Latinx (8,631 cases, 20,351 controls), and African-Americ...

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