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A playbook for harmonization of standards for emergent viral pathogens

Suliman, S.; Fuchs, S.; Catoe, D.; Hansen, L.; Eveleigh, D.; Crone, M. A.; Freemont, P. S.; Kammel, M.; Zeichhardt, H.; Anfora, A. T.; Garlick, R.; Almond, N.; Mark, M.; Beck, B.; Wang, H.; Sharma, K.; Pestano, G.; Vancann, J.; Vandesompele, J.; Corner, A. S.; Albrecht, J. A.; Boles, D. J.; Eisenberg, M. T.; Harris, A. B.; Krueger, B. J.; Suchanek, A. L.; Urban, T. J.; Williams, J.; Chain, P.; Deshpande, A.; Hollander, A.; Chalise, S.; Walt, D. R.; Germer, J.; Yao, J. D.; Pritt, B. S.; Nolte, F. S.; Kosir, A. B.; Milavec, M.; Cleveland, M. H.; Vallone, P. M.; Busby, E. J.; Huggett, J. F.; O'Su

2024-10-06 infectious diseases
10.1101/2024.10.05.24314949 medRxiv
Show abstract

Effective clinical and public health decision-making during a pandemic depends on reliable and interoperable clinical diagnostic test results. To ensure trustworthy outcomes, we need widely available and harmonized calibration standards on a shared scale. We present a playbook for an inter-laboratory harmonization study that calibrates any available standards against a limited-availability standard issued by a global authority like the World Health Organization (WHO).

Published in Accreditation and Quality Assurance · not in our set (fewer than 10 published preprints to learn from) · training set

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