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Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning

Ackerman, D.; Avetissian, E.; Bleck, C. K. E.; Bogovic, J. A.; Innerberger, M.; Korff, W.; Li, W.-P.; Lu, Z.; Petruncio, A.; Preibisch, S.; Qiu, W.; Rhoades, J.; Saalfeld, S.; Silva, M.; Trautman, E. T.; Vorimo, R.; Weigel, A. V.; Yu, Z.; Zubov, Y.; CellMap Project Team,

2024-09-07 cell biology
10.1101/2024.09.05.611438 bioRxiv
Show abstract

This report presents a comprehensive data release exploring the tissue microarchitecture of P7 aged mice using Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) combined with machine learning-based segmentations of nuclei. The study includes high-resolution 3D volumes and nucleus segmentations for seven vital tissues--pancreas, liver, kidney, heart, thymus, hippocampus, and skin--from a single mouse. The detailed datasets are openly accessible onOpenOrganelle.org, providing a valuable resource for the scientific community to support further research and collaboration.

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