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Temporal kinetics of brain state effects on visual perception

Schmid, P.; Klein, T.; Minakowski, P.; Sager, S.; Reichert, C.; Knight, R. T.; Duerschmid, S.

2024-08-06 neuroscience
10.1101/2024.08.02.606289 bioRxiv
Show abstract

We investigated the effects of brain states on human perception and early visual response comparing focused wakefulness (ON state) to external inattention (OFF state). In two experiments, we investigated the temporal kinetics of brain states changes during stimulus processing and assessed fluctuations across extended periods of time. We used a classifier to distinguish between these states on a single trial level using theta activity in MEG sensors. We found that participants shifted from an ON to an OFF state as rapidly as two seconds. Visual target discrimination was comparable in both states, but reaction times were slower and more variable during the OFF state. Broad band high-frequency activity (BHA) recorded in MEG sensors covering the occipital cortex tracked target grating orientation. BHA was reduced during the OFF state but participants were still able to distinguish sensory information highlighting the role of BHA in visual perception across cognitive brain states.

Published in Scientific Reports (predicted rank #2) · training set

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