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Clinical Response to fMRI-guided Compared to Non-Image Guided rTMS in Depression and PTSD: A Randomized Trial
2024-07-31
psychiatry and clinical psychology
Title + abstract only
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BackgroundImage-guided brain stimulation is hypothesized to enhance clinical outcomes but head-to-head comparisons favoring image-guidance are so far lacking. MethodsPTSD/MDD patients were randomized (N=51) to a two-condition sequence in a two period cross-over design. For the first condition, patients were randomized to 10-session rTMS treatment to either a subgenual cingulate (sgACC) functional connectivity cortical target (fMRI-guided) or standard scalp-based target. Additionally, patients w...
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