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Causal Relationship between Mental Disorders and Cancers: a Mendelian Randomization Study
2024-07-24
oncology
Title + abstract only
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BackgroundEvidence from observational studies suggests an association between mental disorders and cancers. However, the causality of this association remains unclear. MethodsWe collected genome-wide association study (GWAS) summary statistics of five mental disorders from the Psychiatric Genomics Consortium (PGC, 72,517 to 500,199 participants), paired with GWAS summary statistics of the risks of 18 cancer types from the UK Biobank (167,020 to 361,194 participants) and FinnGen database (110,52...
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