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Distinct Plasma Protein Profiles Distinguish Faster And Slower Disease Progression In HIV-1 And HIV-2 Infections

2024-07-24 hiv aids Title + abstract only
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The asymptomatic disease stage in HIV-2 infection is approximately twice as long compared to in HIV-1 infection, still the majority of HIV-2 infected individuals progress to AIDS in the absence of antiretroviral treatment. In this study, we applied data-independent acquisition mass spectrometry analysis of blood plasma samples collected from HIV negative, and HIV-1 or HIV-2 infected individuals in Guinea-Bissau with an estimated date of HIV infection, to explore associations between plasma prote...

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