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Evaluating theories of neural information integration during visual search

Leite, A.; Adeli, H.; McPeek, R. M.; Zelinsky, G. J.

2024-07-06 neuroscience
10.1101/2024.07.03.601936 bioRxiv
Show abstract

The brain routes and integrates information from many sources during behavior. A number of models explain this phenomenon within the framework of mixed selectivity theory, yet it is difficult to compare their predictions to understand how neurons and circuits integrate information. In this work, we apply time-series partial information decomposition [PID] to compare models of integration on a dataset of superior colliculus [SC] recordings collected during a multi-target visual search task. On this task, SC must integrate target guidance, bottom-up salience, and previous fixation signals to drive attention. We find evidence that SC neurons integrate these factors in diverse ways, including decision-variable selectivity to expected value, functional specialization to previous fixation, and code-switching (to incorporate new visual input).

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