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High mortality and complications in patients admitted with Takotsubo cardiomyopathy without improvement in outcomes over the years.

Movahed, M. R.; Javanmardi, E.; Hashemzadeh, M.

2024-06-20 cardiovascular medicine
10.1101/2024.06.19.24309204 medRxiv
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IntroductionTakotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. MethodsWe used the Nationwide inpatient sample (NIS) database for our study. We evaluated trends, mortality, and complications of patients admitted with Takotsubo cardiomyopathy from available 2016-2020 years in adults over the age of 18. ResultsA total of 199,890 patients with Takotsubo were found in our database with 83% being female and higher prevalence with age, Caucasian race, and highest income. Mortality was high at 6.5 % with no significant improvement over the years studied. Furthermore, major complications were substantial. Cardiogenic shock occurred in 6.6%, atrial fibrillation in 20.7%, Cardiac arrest in 3.4%, congestive heart failure in 35.9% and stroke in 5.3%. ConclusionTakotsubo cardiomyopathy is associated with high mortality and complications with no improvement in outcome over the 5 years study. Further improvement in care is needed to improve outcomes.

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