Prevalent chromosome fusion in Vibrio cholerae O1
Cuenod, A.; Chac, D.; Khan, A. I.; Chowdhury, F.; Hyppa, R. W.; Markiewicz, S. M.; Calderwood, S. B.; Ryan, E. T.; Harris, J. B.; LaRocque, R. C.; Bhuiyan, T. R.; Smith, G. R.; Qadri, F.; Lypaczewski, P.; Weil, A. A.; Shapiro, B. J.
Show abstract
Two circular chromosomes are a defining feature of the family Vibrionaceae, including the pathogen Vibrio cholerae, with rare reports of isolates with a single, fused chromosome. Here we report chromosome fusions in clinical V. cholerae O1 isolates, including several independent fusion events stable enough to be transmitted between patients within a household. Fusion occurs in a 12 kilobase-pair homologous sequence shared between the two chromosomes, which may lead to reversible chromosomal fusion.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Overlapping transmission of group A and C/G Streptococcus facilitates inter-species mobile genetic element exchange 95%
- Population structure, biogeography and transmissibility of Mycobacterium tuberculosis 94%
- Dual RNA-seq provides insight into the biology of the neglected intracellular human pathogen Orientia tsutsugamushi 94%
Similar papers in this journal
- Gamma-Mobile-Trio systems define a new class of mobile elements rich in bacterial defensive and offensive tools 93%
- Diverse phage defence systems define West African South American pandemic Vibrio cholerae 93%
- The major pathogen Haemophilus influenzae experiences pervasive recombination and purifying selection at local and global scales 93%
Similar papers in this journal
- Evolutionary sweeps of subviral parasites and their phage host bring unique parasite variants and disappearance of a phage CRISPR-Cas system 94%
- Giant transposons promote strain heterogeneity in a major fungal pathogen 94%
- Genomic surveillance of vancomycin-resistant Enterococcus faecium reveals spread of a linear plasmid conferring a nutrient utilization advantage 94%
Similar papers in this journal
- Temperate gut phages are prevalent, diverse, and predominantly inactive 93%
- High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study 93%
- Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin 93%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.