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Insula uses overlapping codes for emotion in self and others

Xiao, J.; Adkinson, J. A.; Allawala, A. B.; Banks, G.; Bartoli, E.; Fan, X.; Mocchi, M.; Pascuzzi, B.; Pulapaka, S.; Franch, M. C.; Mathew, S. J.; Mathura, R. K.; Myers, J.; Pirtle, V.; Provenza, N. R.; Shofty, B.; Watrous, A. J.; Pitkow, X.; Goodman, W. K.; Pouratian, N.; Sheth, S. A.; Bijanki, K. R.; Hayden, B. Y.

2024-06-08 neuroscience
10.1101/2024.06.04.596966 bioRxiv
Show abstract

In daily life, we must recognize others emotions so we can respond appropriately. This ability may rely, at least in part, on neural responses similar to those associated with our own emotions. We hypothesized that the insula, a cortical region near the junction of the temporal, parietal, and frontal lobes, may play a key role in this process. We recorded local field potential (LFP) activity in human neurosurgical patients performing two tasks, one focused on identifying their own emotional response and one on identifying facial emotional responses in others. We found matching patterns of gamma- and high-gamma band activity for the two tasks in the insula. Three other regions (MTL, ACC, and OFC) clearly encoded both self- and other-emotions, but used orthogonal activity patterns to do so. These results support the hypothesis that the insula plays a particularly important role in mediating between experienced vs. observed emotions.

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