The complete genome of lettuce reveals centromere landscape and empowers breeding
Wang, K.; Jin, J.; Wang, J.; Wang, X.; Sun, J.; Meng, D.; Wang, X.; Guo, L.
Show abstract
Lettuce (Lactuca sativa L.) is a globally grown vegetable crop as the most popular salad ingredient. Lettuce breeding is crucial to enhancing yield, nutrition and disease resistance, but impeded by lacking a high-quality genome resource. In addition, the released genomes remain fragmented (with hundreds of gaps) and incomplete with omitting pivotal centromeres and telomeres. Here, we report a 2.59 Gb complete telomere-to-telomere (T2T) genome assembly for lettuce. T2T genome analysis revealed the unique genetic and epigenetic architectures of centromere repeats dominated by retrotransposons and satellites. The complete genome and annotation facilitate the identification of candidate disease resistance (NLR) genes induced during grey mold infection. The genomic resources, and biological insights into genetic and epigenetic landscape of centromeres not only advance lettuce research and breeding, but also propel the biology and evolution of centromeres across plant kingdom.
Matching journals
The top 7 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- A reference genome assembly of the alpine forage grass Elymus nutans 97%
- Chromosome-level Thlaspi arvense genome provides new tools for translational research and for a newly domesticated cash cover crop of the cooler climates 96%
- A Citrullus genus super-pangenome reveals extensive variations in wild and cultivated watermelons and sheds light on watermelon evolution and domestication 96%
Similar papers in this journal
- A gap-free tomato genome built from complementary PacBio and Nanopore long DNA sequences reveals extensive linkage drag during breeding 96%
- Whole Genome Assembly and Annotation of Northern Wild Rice, Zizania palustris L., Supports a Whole Genome Duplication in the Zizania Genus 96%
- Genome and transcriptome architecture of allopolyploid okra (Abelmoschus esculentus) 96%
Similar papers in this journal
- A near-complete genome sequence of einkorn wheat provides insight into the evolution of wheat A subgenomes 97%
- Pan-genome analysis of different morphotypes reveals genomic basis of Brassica oleracea domestication and differential organogenesis 96%
- HEMU: an integrated Andropogoneae comparative genomics database and analysis platform 95%
Similar papers in this journal
Similar papers in this journal
- Telomere-to-telomere, gap-free genome of mung beans (Vigna radiata) provides insights into domestication under structural variation 97%
- Deciphering octoploid strawberry evolution with serial LTR similarity matrices for subgenome partition 96%
- Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomato 94%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.