Immune signaling induced by plant Toll/interleukin-1 receptor (TIR) domains is thermostable
Demont, H.; Rembliere, C.; Deslandes, L.; Bernoux, M.
10.1101/2024.05.13.592950 bioRxivShow abstract
Plant disease is a major threat in agriculture and climate change is predicted to intensify it. Above the optimal plants growth range, plant immunity and in particular immune responses induced by nucleotide-binding leucine rich repeat receptors (NLRs) are dampened, but the underlying molecular mechanisms remains elusive. NLRs usually contain an N-terminal signaling domain, such as Toll/interleukin-1 receptor (TIR) domain, which is self-sufficient to trigger immune signaling. By using inducible Arabidopsis transgenic lines expressing TIR-containing NLRs (TNLs) or corresponding isolated TIR domains from Arabidopsis RPS4 and flax L6 NLRs, we showed that immune signaling induced downstream of TNL activation is not affected by an elevation of temperature. Conditional activation of TNL- and isolated TIR-mediated immune responses follow the same signaling route at permissive temperature (EDS1/RNLs requirement and activation of the salicylic acid sector). Yet, this signaling pathway is maintained under elevated temperature (30{degrees}C) when induced by isolated TIRs, but not full-length TNLs. This work underlines the need to further study how NLRs are impacted by an increase of temperature, which is particularly important to improve the resilience of plant disease resistance in a warming climate.
Matching journals
The top 6 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- THESEUS1 modulates cell wall stiffness and abscisic acid production in Arabidopsis thaliana 96%
- Oligomerisation of a plant helper NLR requires cell-surface and intracellular immune receptor activation 96%
- Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors 96%
Similar papers in this journal
- Shade suppresses wound-induced leaf repositioning through a mechanism involving PHYTOCHROME KINASE SUBSTRATE (PKS) genes 94%
- The helper NLR immune protein NRC3 mediates the hypersensitive cell death caused by the cell-surface receptor Cf-4 94%
- Arabidopsis thaliana natural variation in temperature-modulated immunity uncovers transcription factor UNE12 as a thermoresponsive regulator 94%
Similar papers in this journal
Similar papers in this journal
Similar papers in this journal
- The Xanthomonas type-III effector protein XopS stabilizes CaWRKY40a to regulate defense hormone responses and preinvasion immunity in pepper (Capsicum annuum) 95%
- N-terminally truncated helper NLR NRG1C antagonizes immunity mediated by its full-length neighbors NRG1A and NRG1B 95%
- TOR coordinates nucleotide availability with ribosome biogenesis in plants 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.