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Parallel feedback processing for voluntary control: knowledge of spinal feedback in motor cortex

Guang, H.; Nashed, J. Y.; Pruszynski, J. A.; Kalidindi, H. T.; Crevecoeur, F.; Cross, K. P.; Blohm, G.; Scott, S. H.

2024-05-14 neuroscience
10.1101/2024.05.12.593756 bioRxiv
Show abstract

How hierarchical feedback pathways coordinate goal-directed motor corrections remains unknown. We show that systematic increases in spinal reflex responses to applied loads lead to a reciprocal reduction in the neural response in primary motor cortex. We use a neural network model to highlight how knowledge on lower-level feedback processing (i.e. spinal reflexes) can be embedded into a network to generate goal-directed corrections through parallel feedback pathways.

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