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A novel perspective on equal and cross-frequency neural coupling: integration and segregation of the brain networks' function

Mateos, D. M.; Perez Velazquez, J. L.

2024-05-12 neuroscience
10.1101/2024.05.12.593673 bioRxiv
Show abstract

We introduce a novel perspective in equal and multifrequency coupling derived from considering neuronal synchrony as a possible equivalence relation. The experimental results agree with the theoretical prediction that cross-frequency coupling results in a partition of the brain synchrony state space. We place these results in the framework of the integration and segregation of information in the processing of sensorimotor transformations by the brain cell circuits and propose that equal frequency (1:1) connectivity favours integration of information in the brain whereas cross-frequency coupling (n:m) favours segregation. These observations may provide an outlook about how to reconcile the need for stability in the brains operations with the requirement for diversity of activity in order to process many sensorimotor transformations simultaneously.

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