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Clinical Sampling Of Small Intestine Luminal Content For Microbiome Multi-Omics Analysis: A Performance Analysis Of The Small Intestine Microbiome Aspiration (Simba) Capsule And Benchmarking Against Endoscopy

2024-04-07 gastroenterology Title + abstract only
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ObjectiveThe small intestine (SI) microbiome is increasingly implicated in both functional gastrointestinal (GI) disorders and a wide range of systemic diseases. However, owing to limitations of traditional GI sampling approaches, the SI remains challenging to directly access on a large scale. This work presents the Small Intestinal MicroBiome Aspiration Capsule (SIMBA) as an effective means for sampling SI luminal content. DesignIn an observational clinical study, SIMBA capsules were ingested ...

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