Back

Predictive Modeling for Diabetes Using GraphLIME

Costi, F.; Onchis, D.; Hogea, E.; Istin, C.

2024-03-15 endocrinology
10.1101/2024.03.14.24304281 medRxiv
Show abstract

The purpose of this paper is to present a detailed investigation of the advantages of employing GraphLIME (Local Interpretable Model Explanations for Graph Neural Networks) for the trustworthy prediction of diabetes mellitus. Our pursuit involves identifying the strengths of GraphLIME combined with the attention-mechanism over the standard coupling of deep learning neural networks with the original LIME method. The system build this way, provided us a proficient method for extracting the most relevant features and applying the attention mechanism exclusively to those features. We have closely monitored the performance metrics of the two approaches and conducted a comparative analysis. Leveraging attention mechanisms, we have achieved an accuracy of 92.6% for the addressed problem. The models performance is meticulously demonstrated throughout the study, and the results are furthermore evaluated using the Receiver Operating Characteristic (ROC) curve. By implementing this technique on a dataset of 768 patients diagnosed with or without diabetes mellitus, we have successfully boosted the models performance by over 18%.

Matching journals

The top 5 journals account for 50% of the predicted probability mass.

1
Expert Systems with Applications
11 papers in training set
Top 0.1%
22.6%
2
Biology Methods and Protocols
61 papers in training set
Top 0.1%
9.0%
3
PLOS Digital Health
106 papers in training set
Top 0.6%
9.0%
4
PLOS ONE
5266 papers in training set
Top 27%
5.6%
5
JAMIA Open
42 papers in training set
Top 0.3%
5.5%
50% of probability mass above
6
JMIRx Med
32 papers in training set
Top 0.1%
5.5%
7
Informatics in Medicine Unlocked
22 papers in training set
Top 0.2%
4.4%
8
Computational and Structural Biotechnology Journal
242 papers in training set
Top 1%
3.6%
9
Scientific Reports
3612 papers in training set
Top 29%
3.5%
10
Journal of Biomedical Informatics
47 papers in training set
Top 0.5%
3.3%
11
JMIR Medical Informatics
18 papers in training set
Top 0.3%
2.7%
12
Computers in Biology and Medicine
128 papers in training set
Top 2%
2.1%
13
Heliyon
152 papers in training set
Top 3%
1.7%
14
JMIR Public Health and Surveillance
45 papers in training set
Top 0.7%
1.7%
15
IEEE Journal of Biomedical and Health Informatics
37 papers in training set
Top 0.7%
1.5%
16
Journal of Pathology Informatics
15 papers in training set
Top 0.2%
1.5%
17
Frontiers in Physiology
106 papers in training set
Top 2%
1.0%
18
Computer Methods and Programs in Biomedicine
28 papers in training set
Top 0.9%
1.0%
19
Journal of the American Medical Informatics Association
71 papers in training set
Top 2%
1.0%
20
IEEE Access
35 papers in training set
Top 1%
1.0%
21
PLOS Global Public Health
344 papers in training set
Top 7%
0.9%
22
BMC Medical Informatics and Decision Making
43 papers in training set
Top 2%
0.9%
23
International Journal of Environmental Research and Public Health
128 papers in training set
Top 6%
0.6%
24
DIGITAL HEALTH
17 papers in training set
Top 1%
0.6%
25
IEEE/ACM Transactions on Computational Biology and Bioinformatics
38 papers in training set
Top 1%
0.6%
26
Computational Biology and Chemistry
28 papers in training set
Top 1%
0.6%