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Intensive Blood Pressure Lowering Improves Left Ventricular Geometry in Older Hypertensive Patients: The STEP Trial

2024-04-01 cardiovascular medicine Title + abstract only
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BackgroundThe effect of intensive systolic blood pressure (SBP) lowering on left ventricular (LV) geometry remains unclear. MethodsPatients with hypertension aged 60-80 years without prior stroke were enrolled from 42 centers across China from January 2017. Eligible patients were randomly assigned to intensive (target: 110 to <130 mmHg) or standard (target: 130 to < 150 mmHg) SBP-lowering treatment. LV mass (LVM) was assessed by two-dimensional, M-mode, color flow Doppler echocardiography. LV h...

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