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Enhanced 40 and 80 Hz Auditory Steady State Responses in Idiopathic Tinnitus

Ghasemahmad, Z.; Mahmoudian, S.; Gavazzi, D.; Jalaei, S.; Farahani, S.

2024-03-04 otolaryngology
10.1101/2024.03.02.24303654 medRxiv
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ObjectivesThis study aimed to investigate changes in auditory processing using auditory steady state responses (ASSR) in patients with idiopathic tinnitus. Method19 tinnitus patients and 23 control subjects without tinnitus were examined with multiple ASSR. Three modulation frequencies of 20, 40, and 80 HZ were tested and the steady state responses were compared between tinnitus and control group. Further, the thresholds in ipsi- and contralateral side to ear with tinnitus were compared. ResultsOur findings showed no significant difference in ASSR thresholds in ipsi- and contralateral side in tinnitus patients. However, we observed enhanced ASSRs at 40 and 80 Hz modulations in patients with idiopathic tinnitus compared to no-tinnitus control subjects. ConclusionsThe results of this study suggest possible sensory deficits along higher order auditory regions in patients with idiopathic tinnitus. Further, our data indicates a bilateral involvement of auditory pathway in these regions in patients with lateralized tinnitus.

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