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Stability from subspace rotations and traveling waves

Batabyal, T.; Brincat, S. L.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M. K.; Miller, E. K.

2024-02-19 neuroscience
10.1101/2024.02.19.581020 bioRxiv
Show abstract

Cortical activity shows the ability to recover from distractions. We analyzed neural activity from the prefrontal cortex (PFC) of monkeys performing working memory tasks with mid-memory-delay distractions (a cued gaze shift or an irrelevant visual input). After distraction there were state-space rotational dynamics that returned spiking to population patterns similar to those pre-disruption. In fact, rotations were fuller when the task was performed correctly versus when errors were made. We found a correspondence between state-space rotations and traveling waves across the surface of the PFC. This suggests a role for emergent dynamics like state-space rotations and traveling waves in recovery from distractions.

Published in Journal of Cognitive Neuroscience (predicted rank #22) · training set

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