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Multi-trait genetic analysis identifies novel pleiotropic loci for depression and SCZ in East Asians

2024-01-30 genetic and genomic medicine Title + abstract only
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While genetic correlations, pleiotropic loci, and shared genetic mechanisms of psychiatric disorders have been extensively studied in European populations, the investigation of these factors in East Asian populations has been relatively limited. To identify novel pleiotropic risk loci for depression and schizophrenia (SCZ) in East Asians. We harnessed the most comprehensive dataset available for East Asians and quantified the genetic overlap between depression, SCZ, and their related traits via ...

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